USB bootable image GenomicOS is built using Debian’s live-build, enabling persistent or ephemeral deployment from a single ISO image.
Pre-configured Genomics Toolkit
GenomicOS ships with a comprehensive, ready-to-run toolchain:
| Category | Highlighted Tools |
|---|---|
| Quality control | FastQC · MultiQC … |
| Sequence alignment | BWA · Bowtie2 · STAR … |
| Variant calling & annotation | OakVar · GATK · VEP · ANNOVAR · dbSNP … |
| Visualization | IGV · UCSC Genome Browser … |
| AI-powered analysis | Machine-learning models for disease-risk assessment & phenotypic insight |
Utilities & Infrastructure
| Area | Tools / Projects |
|---|---|
| Build / Deployment | tenv (OpenTofu) · Conda · Micromamba |
| Workflow orchestration | Cloudgene 3 · Just-DNA-Seq |
| Specialised pipelines | DeepTrio · Pseudo-alignment with kallisto |
| AI & LLMs | Claude-Code completion · vLLM runtime · Evo (GenAI for genomes) · LongevityGenie |
| Genotyping & imputation | Michigan Imputation Server 2 · T2T reference builds |
| Variant analysis extras | Demuxlet (sample identity) · Lineage (clonal tracking) |
Bioinformatics Suite
- UGENE (https://ugene.net/) — visual workbench for sequence alignment and assembly.
- NCBI toolkit — offline BLAST databases and Entrez utilities.
- Ready‑to‑run notebooks for longevity marker discovery, and more.